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High Affinity, Developability and Functional Size: The Holy Grail of Combinatorial Antibody Library Generation
Since the initial description of phage display technology for the generation of human antibodies, a variety of selection methods has been developed. The most critical parameter for all in vitro-based approaches is the quality of the antibody library. Concurrent evolution of the libraries has allowed...
Autores principales: | Ponsel, Dirk, Neugebauer, Julia, Ladetzki-Baehs, Kathrin, Tissot, Kathrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263270/ https://www.ncbi.nlm.nih.gov/pubmed/21540796 http://dx.doi.org/10.3390/molecules16053675 |
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