Chemistry and Structure-Activity Relationship of the Styrylquinoline-Type HIV Integrase Inhibitors

In spite of significant progress in anti-HIV-1 therapy, current antiviral chemo-therapy still suffers from deleterious side effects and emerging drug resistance. Therefore, the development of novel antiviral drugs remains a crucial issue for the fight against AIDS. HIV-1 integrase is a key enzyme in...

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Detalles Bibliográficos
Autores principales: Mouscadet, Jean-François, Desmaële, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263292/
https://www.ncbi.nlm.nih.gov/pubmed/20657464
http://dx.doi.org/10.3390/molecules15053048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263292/
https://www.ncbi.nlm.nih.gov/pubmed/20657464
http://dx.doi.org/10.3390/molecules15053048

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