Cargando…
A Regioselective Synthesis of E-Guggulsterone
We have successfully prepared E-guggulsterone from 16,17-epoxy-pregnenolone in 84% yield over two steps via a hydrazine reduction and Oppenhauer oxidation. Additionally, isomerization was induced by heat, light (hν) and acid catalysis to convert E- guggulsterone into the corresponding Z isomer.
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263345/ http://dx.doi.org/10.3390/molecules16054165 |