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A Regioselective Synthesis of E-Guggulsterone

We have successfully prepared E-guggulsterone from 16,17-epoxy-pregnenolone in 84% yield over two steps via a hydrazine reduction and Oppenhauer oxidation. Additionally, isomerization was induced by heat, light (hν) and acid catalysis to convert E- guggulsterone into the corresponding Z isomer.

Detalles Bibliográficos
Autores principales:	Ham, Jungyeob, Chin, Jungwook, Kang, Heonjoong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2011
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263345/ http://dx.doi.org/10.3390/molecules16054165

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