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Dynamic control of endogenous metabolism with combinatorial logic circuits

Controlling gene expression during a bioprocess enables real‐time metabolic control, coordinated cellular responses, and staging order‐of‐operations. Achieving this with small molecule inducers is impractical at scale and dynamic circuits are difficult to design. Here, we show that the same set of s...

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Detalles Bibliográficos
Autores principales: Moser, Felix, Espah Borujeni, Amin, Ghodasara, Amar N., Cameron, Ewen, Park, Yongjin, Voigt, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263354/
https://www.ncbi.nlm.nih.gov/pubmed/30482789
http://dx.doi.org/10.15252/msb.20188605