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MDL-28170 Has No Analgesic Effect on CCI Induced Neuropathic Pain in Mice

The calpain inhibitor MDL-28710 blocks the early local pro-inflammatory cytokine gene expression in mice after chronic constriction nerve injury (CCI). One-hundred-thirteen wild type mice of C57Bl/6J background received CCI of the right sciatic nerve. Mechanical paw withdrawal thresholds and thermal...

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Detalles Bibliográficos
Autores principales: Üçeyler, Nurcan, Biko, Lydia, Sommer, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263360/
https://www.ncbi.nlm.nih.gov/pubmed/20657463
http://dx.doi.org/10.3390/molecules15053038