A Screening of a Library of T7 Phage-Displayed Peptide Identifies E2F-4 as an Etoposide-Binding Protein

Etoposide (VP-16) is an anti-tumor compound that targets topoisomerase II (top II). In this study, we have identified an alternative binding protein of etoposide by screening a library of T7 phage-displayed peptides. After four rounds of selection using a biotinylated etoposide derivative immobilize...

Descripción completa

Detalles Bibliográficos
Autores principales: Takami, Mihoko, Takakusagi, Yoichi, Kuramochi, Kouji, Tsukuda, Senko, Aoki, Satoko, Morohashi, Kengo, Ohta, Keisuke, Kobayashi, Susumu, Sakaguchi, Kengo, Sugawara, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263361/
https://www.ncbi.nlm.nih.gov/pubmed/21610657
http://dx.doi.org/10.3390/molecules16054278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263361/
https://www.ncbi.nlm.nih.gov/pubmed/21610657
http://dx.doi.org/10.3390/molecules16054278

Ejemplares similares