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Different tau species lead to heterogeneous tau pathology propagation and misfolding

Tauopathies are a heterogeneous group of pathologies characterized by tau aggregation inside neurons. Most of them are sporadic but certain tauopathies rely on tau gene (MAPT) mutations. They particularly differ from one to another by their different neuropathological signatures e.g. lesion shapes,...

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Detalles Bibliográficos
Autores principales: Dujardin, Simon, Bégard, Séverine, Caillierez, Raphaëlle, Lachaud, Cédrick, Carrier, Sébastien, Lieger, Sarah, Gonzalez, Jose A., Deramecourt, Vincent, Déglon, Nicole, Maurage, Claude-Alain, Frosch, Matthew P., Hyman, Bradley T., Colin, Morvane, Buée, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263555/
https://www.ncbi.nlm.nih.gov/pubmed/30497516
http://dx.doi.org/10.1186/s40478-018-0637-7