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Pharmacokinetic‐Pharmacodynamic Model of Neutropenia in Patients With Myeloma Receiving High‐Dose Melphalan for Autologous Stem Cell Transplant

High‐dose melphalan (HDM) is part of the conditioning regimen in patients with multiple myeloma (MM) receiving autologous stem cell transplantation (ASCT). However, individual sensitivity to melphalan varies, and many patients experience severe toxicities. Prolonged severe neutropenia is one of the...

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Detalles Bibliográficos
Autores principales: Cho, Yu Kyoung, Irby, Donald J., Li, Junan, Sborov, Douglas W., Mould, Diane R., Badawi, Mohamed, Dauki, Anees, Lamprecht, Misty, Rosko, Ashley E., Fernandez, Soledad, Hade, Erinn M., Hofmeister, Craig C., Poi, Ming, Phelps, Mitch A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263666/
https://www.ncbi.nlm.nih.gov/pubmed/30343510
http://dx.doi.org/10.1002/psp4.12345