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A discontinuous Galerkin model for fluorescence loss in photobleaching of intracellular polyglutamine protein aggregates
BACKGROUND: Intracellular phase separation and aggregation of proteins with extended poly-glutamine (polyQ) stretches are hallmarks of various age-associated neurodegenerative diseases. Progress in our understanding of such processes heavily relies on quantitative fluorescence imaging of suitably ta...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264036/ https://www.ncbi.nlm.nih.gov/pubmed/30519460 http://dx.doi.org/10.1186/s13628-018-0046-0 |