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A discontinuous Galerkin model for fluorescence loss in photobleaching of intracellular polyglutamine protein aggregates

BACKGROUND: Intracellular phase separation and aggregation of proteins with extended poly-glutamine (polyQ) stretches are hallmarks of various age-associated neurodegenerative diseases. Progress in our understanding of such processes heavily relies on quantitative fluorescence imaging of suitably ta...

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Detalles Bibliográficos
Autores principales: Hansen, Christian V., Schroll, Hans J., Wüstner, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264036/
https://www.ncbi.nlm.nih.gov/pubmed/30519460
http://dx.doi.org/10.1186/s13628-018-0046-0