Schiff Bases of Indoline-2,3-dione: Potential Novel Inhibitors of Mycobacterium Tuberculosis (Mtb) DNA Gyrase (†)

In the present study a series of Schiff bases of indoline-2,3-dione were synthesized and investigated for their Mtb gyrase inhibitory activity. Promising inhibitory activity was demonstrated with some of these derivatives, which exhibited IC(50) values ranging from 50–157 μM. The orientation and the...

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Detalles Bibliográficos
Autores principales: Aboul-Fadl, Tarek, Abdel-Aziz, Hatem A., Abdel-Hamid, Mohammed K., Elsaman, Tilal, Thanassi, Jane, Pucci, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264139/
https://www.ncbi.nlm.nih.gov/pubmed/22143547
http://dx.doi.org/10.3390/molecules16097864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264139/
https://www.ncbi.nlm.nih.gov/pubmed/22143547
http://dx.doi.org/10.3390/molecules16097864

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