Pharmaceutical Composition of Hydrochlorothiazide:β-Cyclo-dextrin: Preparation by Three Different Methods, Physico-Chemical Characterization and In Vivo Diuretic Activity Evaluation

Hydrochlorothiazide is a common diuretic antihypertensive drug of the thiazide family. Its poor aqueous solubility is one of the reasons for its limited bioavailability after oral administration. This work aimed at the development of a hydrochlorothiazide:β-cyclodextrin (HTZ:β-CD) pharmaceutical com...

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Detalles Bibliográficos
Autores principales: Pires, Maria Arlete Silva, Souza dos Santos, Robson Augusto, Sinisterra, Rubén Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264165/
https://www.ncbi.nlm.nih.gov/pubmed/21623317
http://dx.doi.org/10.3390/molecules16064482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264165/
https://www.ncbi.nlm.nih.gov/pubmed/21623317
http://dx.doi.org/10.3390/molecules16064482

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