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Facile Synthesis of Functionalized Spiropyrrolizidine Oxindoles via a Three-Component Tandem Cycloaddition Reaction

An efficient synthesis of functionalized spiropyrrolizidine oxindoles via a three-component tandem cycloaddition has been achieved. This strategy can provide direct and rapid access to spiropyrrolizidine oxindoles in high yields (up to 99%) with excellent diastereoselectivities (up to 99:1 dr). The...

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Detalles Bibliográficos
Autores principales: Xie, Yong-Mei, Yao, Yu-Qin, Sun, Hong-Bao, Yan, Ting-Ting, Liu, Jie, Kang, Tai-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264231/
http://dx.doi.org/10.3390/molecules16108745