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Thymidine Analogues for Tracking DNA Synthesis

Replicating cells undergo DNA synthesis in the highly regulated, S-phase of the cell cycle. Analogues of the pyrimidine deoxynucleoside thymidine may be inserted into replicating DNA, effectively tagging dividing cells allowing their characterisation. Tritiated thymidine, targeted using autoradiogra...

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Detalles Bibliográficos
Autores principales: Cavanagh, Brenton L., Walker, Tom, Norazit, Anwar, Meedeniya, Adrian C.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264245/
https://www.ncbi.nlm.nih.gov/pubmed/21921870
http://dx.doi.org/10.3390/molecules16097980