Synthesis and Antimalarial Activity of Novel Dihydro-Artemisinin Derivatives

The Plasmodium falciparum cysteine protease falcipain-2, one of the most promising targets for antimalarial drug design, plays a key role in parasite survival as a major peptide hydrolase within the hemoglobin degradation pathway. In this work, a series of novel dihydroartemisinin derivatives based...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Cui, Kunqiang, Lu, Weiqiang, Luo, Wei, Wang, Jian, Huang, Jin, Guo, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264262/
https://www.ncbi.nlm.nih.gov/pubmed/21629181
http://dx.doi.org/10.3390/molecules16064527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264262/
https://www.ncbi.nlm.nih.gov/pubmed/21629181
http://dx.doi.org/10.3390/molecules16064527

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