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The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases

Polyketides are a diverse class of medically important natural products whose biosynthesis is catalysed by polyketide synthases (PKSs), in a fashion highly analogous to fatty acid biosynthesis. In modular PKSs, the polyketide chain is assembled by the successive condensation of activated carboxylic...

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Detalles Bibliográficos
Autores principales: Kwan, David H., Schulz, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264292/
https://www.ncbi.nlm.nih.gov/pubmed/21775938
http://dx.doi.org/10.3390/molecules16076092