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Studies on Log P(o/w) of Quinoxaline di-N-Oxides: A Comparison of RP-HPLC Experimental and Predictive Approaches
As reported in our previous papers, a series of quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives were synthesized and studied as anti-tuberculosis agents. Here, the capability of the shake-flask method was studied and the retention time (expressed as log K) of 20 compounds were determined by RP-...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264295/ https://www.ncbi.nlm.nih.gov/pubmed/22143549 http://dx.doi.org/10.3390/molecules16097893 |