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Studies on Log P(o/w) of Quinoxaline di-N-Oxides: A Comparison of RP-HPLC Experimental and Predictive Approaches

As reported in our previous papers, a series of quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives were synthesized and studied as anti-tuberculosis agents. Here, the capability of the shake-flask method was studied and the retention time (expressed as log K) of 20 compounds were determined by RP-...

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Detalles Bibliográficos
Autores principales:	Moreno, Elsa, Gabano, Elisabetta, Torres, Enrique, Platts, James A., Ravera, Mauro, Aldana, Ignacio, Monge, Antonio, Pérez-Silanes, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264295/ https://www.ncbi.nlm.nih.gov/pubmed/22143549 http://dx.doi.org/10.3390/molecules16097893

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