Cargando…

1,3-Substituted Imidazolidine-2,4,5-triones: Synthesis and Inhibition of Cholinergic Enzymes

A series of novel and highly active acetylcholinesterase and butyrylcholinesterase inhibitors derived from substituted benzothiazoles containing an imidazolidine-2,4,5-trione moiety were synthesized and characterized. The molecular structure of 1-(2,6-diisopropyl-phenyl)-3-[(1R)-1-(6-fluoro-1,3-benz...

Descripción completa

Detalles Bibliográficos
Autores principales: Pejchal, Vladimir, Stepankova, Sarka, Padelkova, Zdenka, Imramovsky, Ales, Jampilek, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264296/
https://www.ncbi.nlm.nih.gov/pubmed/21894089
http://dx.doi.org/10.3390/molecules16097565