Synthesis and Pharmacological Activity of Diterpenylnaphthoquinone Derivatives

New diterpenylquinones, combining a diterpene diacid and a naphthoquinone, were prepared from junicedric acid and lapachol. The new derivatives were assessed as gastroprotective agents by the HCl-EtOH-induced gastric lesions model in mice as well as for basal cytotoxicity on the following human cell...

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Detalles Bibliográficos
Autores principales: Pertino, Mariano Walter, Theoduloz, Cristina, Palenzuela, Jose Antonio, del Mar Afonso, Maria, Yesilada, Erdem, Monsalve, Francisco, González, Paulo, Droguett, Daniel, Schmeda-Hirschmann, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264310/
https://www.ncbi.nlm.nih.gov/pubmed/21996716
http://dx.doi.org/10.3390/molecules16108614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264310/
https://www.ncbi.nlm.nih.gov/pubmed/21996716
http://dx.doi.org/10.3390/molecules16108614

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