Ru/Me-BIPAM-Catalyzed Asymmetric Addition of Arylboronic Acids to Aliphatic Aldehydes and α-Ketoesters

A ruthenium-catalyzed asymmetric arylation of aliphatic aldehydes and α-ketoesters with arylboronic acids has been developed, giving chiral alkyl(aryl)methanols and α-hydroxy esters in good yields. The use of a chiral bidentate phosphoramidite ligand (Me-BIPAM) achieved excellent enantioselectivitie...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamoto, Yasunori, Shirai, Tomohiko, Watanabe, Momoko, Kurihara, Kazunori, Miyaura, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264355/
https://www.ncbi.nlm.nih.gov/pubmed/21694668
http://dx.doi.org/10.3390/molecules16065020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264355/
https://www.ncbi.nlm.nih.gov/pubmed/21694668
http://dx.doi.org/10.3390/molecules16065020

Ejemplares similares