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Targeting Oncogenic Protein-Protein Interactions by Diversity Oriented Synthesis and Combinatorial Chemistry Approaches

We are currently witnessing a decline in the development of efficient new anticancer drugs, despite the salient efforts made on all fronts of cancer drug discovery. This trend presumably relates to the substantial heterogeneity and the inherent biological complexity of cancer, which hinder drug deve...

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Detalles Bibliográficos
Autores principales: Tzakos, Andreas G., Fokas, Demosthenes, Johannes, Charlie, Moussis, Vassilios, Hatzimichael, Eleftheria, Briasoulis, Evangelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264371/
https://www.ncbi.nlm.nih.gov/pubmed/21623312
http://dx.doi.org/10.3390/molecules16064408