Receptor-Based Virtual Screening of EGFR Kinase Inhibitors from the NCI Diversity Database

Epidermal growth factor receptor (EGFR) abnormalities have been associated with several types of human cancer. The crystal structures of its tyrosine kinase domain (EGFR-TK) complexed with small molecule inhibitors revealed the kinase inhibition modes, prompting us to search for novel anti-cancer dr...

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Detalles Bibliográficos
Autores principales: Choowongkomon, Kiattawee, Sawatdichaikul, Orathai, Songtawee, Napat, Limtrakul, Jumras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264413/
https://www.ncbi.nlm.nih.gov/pubmed/20657425
http://dx.doi.org/10.3390/molecules15064041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264413/
https://www.ncbi.nlm.nih.gov/pubmed/20657425
http://dx.doi.org/10.3390/molecules15064041

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