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Evaluation of the Effects of Mitragyna speciosa Alkaloid Extract on Cytochrome P450 Enzymes Using a High Throughput Assay

The extract from Mitragyna speciosa has been widely used as an opium substitute, mainly due to its morphine-like pharmacological effects. This study investigated the effects of M. speciosa alkaloid extract (MSE) on human recombinant cytochrome P450 (CYP) enzyme activities using a modified Crespi met...

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Detalles Bibliográficos
Autores principales: Kong, Wai Mun, Chik, Zamri, Ramachandra, Murali, Subramaniam, Umarani, Aziddin, Raja Elina Raja, Mohamed, Zahurin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264431/
https://www.ncbi.nlm.nih.gov/pubmed/21876481
http://dx.doi.org/10.3390/molecules16097344