Synthesis of Key Fragments of Amphidinolide Q — A Cytotoxic 12-membered Macrolide

β-Hydroxy aldehyde and alkyl ketone moieties were effectively synthesized as key intermediates of amphidinolide Q, a cytotoxic macrolide from the cultured dinoflagellate Amphidinium sp.. The asymmetric center of the former derivative was produced by Sharpless asymmetric epoxidation, followed by E-se...

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Detalles Bibliográficos
Autores principales: Kawa, Kohei, Hara, Akihiro, Ishikawa, Yuichi, Nishiyama, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264435/
https://www.ncbi.nlm.nih.gov/pubmed/21709623
http://dx.doi.org/10.3390/molecules16075422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264435/
https://www.ncbi.nlm.nih.gov/pubmed/21709623
http://dx.doi.org/10.3390/molecules16075422

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