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Synthesis and Cytotoxic Evaluation of Novel N-Methyl-4-phenoxypicolinamide Derivatives

A series of N-methyl-4-phenoxypicolinamide derivatives were synthesized and evaluated in vitro for their cytotoxic activity against A549, H460 and HT29 cell lines. Pharmacological data indicated that some of the target compounds possessed marked antiproliferative activity, superior to that of the re...

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Detalles Bibliográficos
Autores principales: Li, Wei, Zhai, Xin, Ding, Lu, Sun, Limin, Chen, Xiaomei, Gong, Ping, Sun, Tiemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264436/
https://www.ncbi.nlm.nih.gov/pubmed/21694676
http://dx.doi.org/10.3390/molecules16065130