Cargando…

Synthesis and Cytotoxic Evaluation of Novel N-Methyl-4-phenoxypicolinamide Derivatives

A series of N-methyl-4-phenoxypicolinamide derivatives were synthesized and evaluated in vitro for their cytotoxic activity against A549, H460 and HT29 cell lines. Pharmacological data indicated that some of the target compounds possessed marked antiproliferative activity, superior to that of the re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Wei, Zhai, Xin, Ding, Lu, Sun, Limin, Chen, Xiaomei, Gong, Ping, Sun, Tiemin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264436/ https://www.ncbi.nlm.nih.gov/pubmed/21694676 http://dx.doi.org/10.3390/molecules16065130

Ejemplares similares

Discovery of Hybrid Dual N-Acylhydrazone and Diaryl Urea Derivatives as Potent Antitumor Agents: Design, Synthesis and Cytotoxicity Evaluation
por: Zhai, Xin, et al.
Publicado: (2013)

Synthesis and Cytotoxicity of Novel 10-Substituted Dihydroartemisinin Derivatives Containing N-Arylphenyl-ethenesulfonamide Groups
por: Liu, Yajing, et al.
Publicado: (2013)

Synthesis, Antiviral and Cytotoxicity Studies of Novel N-substituted Indophenazine Derivatives
por: Selvam, P., et al.
Publicado: (2012)

Synthesis, Characterization and Cytotoxicity of Alkylated Quercetin Derivatives
por: Bao, Xin-Ran, et al.
Publicado: (2016)

Synthesis and Cytotoxicity Evaluation of Naphthalimide Derived N-Mustards
por: Lou, Qinghua, et al.
Publicado: (2014)

Synthesis and Cytotoxicity of Novel Hexahydrothieno-cycloheptapyridazinone Derivatives
por: Pau, Amedeo, et al.
Publicado: (2009)

Synthesis and Tumor Cytotoxicity of Novel Amide Derivatives of β-Hederin
por: Liu, Yang, et al.
Publicado: (2010)

Synthesis and Cytotoxic Activity of Novel Tetrahydrocurcumin Derivatives Bearing Pyrazole Moiety
por: Mahal, Ahmed, et al.
Publicado: (2017)

Synthesis and cytotoxic activities of novel 4-methoxy-substituted and 5-methyl-substituted (3′S,4′S)-(−)-cis-khellactone derivatives that induce apoptosis via the intrinsic pathway
por: Chen, Jingrun, et al.
Publicado: (2017)

Synthesis, Cytotoxicity, and Antileishmanial Activity of N,N'-Disubstituted Ethylenediamine and Imidazolidine Derivatives
por: de Carvalho, Gustavo S. G., et al.
Publicado: (2010)

Synthesis and in vitro Cytotoxicity of Novel Ursolic Acid Derivatives
por: Meng, Yanqiu, et al.
Publicado: (2010)

Design, Synthesis and Evaluation of Novel Derivatives of Curcuminoids with Cytotoxicity
por: Chen, Chen-Yin, et al.
Publicado: (2021)

Synthesis and Cytotoxicity Evaluation of Tropinone Derivatives
por: Yin, Xiu-Juan, et al.
Publicado: (2017)

Synthesis and Cytotoxic Activity of Some Novel N-Pyridinyl-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide Derivatives
por: Ding, Huaiwei, et al.
Publicado: (2012)

Synthesis and Biological Evaluation of Novel N-Methyl-picolinamide-4-thiol Derivatives as Potential Antitumor Agents
por: Huang, Ting-Ting, et al.
Publicado: (2012)

Synthesis and Cytotoxic Activity Study of Novel 2-(Aryldiazenyl)-3-methyl-1H-benzo[g]indole Derivatives
por: Arafeh, Manar M., et al.
Publicado: (2021)

Synthesis and Cytotoxicities of Royleanone Derivatives
por: Li, Cheng-Ji, et al.
Publicado: (2018)

Cytotoxicity against HL60 Cells of Ficifolidione Derivatives with Methyl, n-Pentyl, and n-Heptyl Groups
por: Nishiwaki, Hisashi, et al.
Publicado: (2019)

2-(4-Fluorophenyl)-N-phenylacetamide Derivatives as Anticancer Agents: Synthesis and In-vitro Cytotoxicity Evaluation
por: Aliabadi, Alireza, et al.
Publicado: (2013)

Design, synthesis, cytotoxic activity, and apoptosis inducing effects of 4- and N-substituted benzoyltaurinamide derivatives
por: AKGÜL, Özlem, et al.
Publicado: (2020)

Synthesis and Cytotoxic Activity of Novel C-23-Modified Asiatic Acid Derivatives
por: Lu, Yi-hong, et al.
Publicado: (2020)

Synthesis, antiviral, cytotoxic and cytostatic evaluation of N(1)-(phosphonoalkyl)uracil derivatives
por: Rygielska-Tokarska, Dorota, et al.
Publicado: (2016)

Design, Synthesis, and Cytotoxicity of Perbutyrylated Glycosides of 4β-Triazolopodophyllotoxin Derivatives
por: Zi, Cheng-Ting, et al.
Publicado: (2015)

Synthesis, Characterization and Cytotoxicity of New Rotundic Acid Derivatives
por: He, Yu-Fang, et al.
Publicado: (2012)

Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives
por: Zhang, Haiwen, et al.
Publicado: (2008)

Synthesis and Cytotoxic Evaluation of Novel 3-Substituted Derivatives of 2-Indolinone
por: Mokhtari, Shaya, et al.
Publicado: (2012)

Synthesis and cytotoxic evaluation of novel quinazolinone derivatives as potential anticancer agents
por: Poorirani, Safoora, et al.
Publicado: (2018)

Design, Synthesis and Biological Evaluation of Novel Piperazinone Derivatives as Cytotoxic Agents
por: Ghasemi, Saeed, et al.
Publicado: (2020)

Synthesis of some novel dibromo-2-arylquinazolinone derivatives as cytotoxic agents
por: Faghih, Zeinab, et al.
Publicado: (2019)

Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists
por: Turnaturi, Rita, et al.
Publicado: (2018)

Conjugates of methylated cyclodextrin derivatives and hydroxyethyl starch (HES): Synthesis, cytotoxicity and inclusion of anaesthetic actives
por: Markenstein, Lisa, et al.
Publicado: (2014)

N-Phenyl-2-p-tolylthiazole-4-carboxamide derivatives: Synthesis and cytotoxicity evaluation as anticancer agents
por: Mohammadi-Farani, Ahmad, et al.
Publicado: (2014)

Methyl N-phenyl carbamate synthesis over Zn/Al/Ce mixed oxide derived from hydrotalcite-like precursors
por: Kang, Min, et al.
Publicado: (2019)

Synthesis, Crystal Structure, Absolute Configuration and Antitumor Activity of the Enantiomers of 5-Bromo-2-chloro-N-(1-phenylethyl)pyridine-3-sulfonamide
por: Zhou, Zhixu, et al.
Publicado: (2015)

Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity
por: Zi, Cheng-Ting, et al.
Publicado: (2019)

Design, synthesis and cytotoxic evaluation of novel betulonic acid-diazine derivatives as potential antitumor agents
por: Shu, Yisong, et al.
Publicado: (2022)

Synthesis and cytotoxic properties of novel (E)-3-benzylidene-7-methoxychroman-4-one derivatives
por: Noushini, Saeedeh, et al.
Publicado: (2013)

Synthesis and cytotoxic evaluation of novel quinozalinone derivatives with substituted benzimidazole in position 3
por: Taherian, Elham, et al.
Publicado: (2019)

Synthesis, Cytotoxic Activity and In Silico Study of Novel Dihydropyridine Carboxylic Acids Derivatives
por: Ballinas-Indilí, Ricardo, et al.
Publicado: (2023)

Synthesis, Characterization, and Cytotoxicity Studies of N-(4-Methoxybenzyl) Thiosemicarbazone Derivatives and Their Ruthenium(II)-p-cymene Complexes
por: Martínez-Estévez, Mónica, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_o997pdbmj5l5fgakn3emaom8in