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Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet)

5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet), an indole-3-carbinol (I3C) metabolite endowed with anticancer properties, is poorly soluble in the solvents most frequently used in biological tests. This study indicates that the use of γ-cyclodextrin (γ-...

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Detalles Bibliográficos
Autores principales: Lucarini, Simone, Santi, Mauro De, Antonietti, Francesca, Brandi, Giorgio, Diamantini, Giuseppe, Fraternale, Alessandra, Paoletti, Maria Filomena, Tontini, Andrea, Magnani, Mauro, Duranti, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264452/
https://www.ncbi.nlm.nih.gov/pubmed/20657428
http://dx.doi.org/10.3390/molecules15064085