Exploiting the Nucleotide Substrate Specificity of Repair DNA Polymerases To Develop Novel Anticancer Agents

The genome is constantly exposed to mutations that can originate during replication or as a result of the action of both endogenous and/or exogenous damaging agents [such as reactive oxygen species (ROS), UV light, genotoxic environmental compounds, etc.]. Cells have developed a set of specialized m...

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Detalles Bibliográficos
Autores principales: Crespan, Emmanuele, Garbelli, Anna, Amoroso, Alessandra, Maga, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264456/
https://www.ncbi.nlm.nih.gov/pubmed/21926946
http://dx.doi.org/10.3390/molecules16097994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264456/
https://www.ncbi.nlm.nih.gov/pubmed/21926946
http://dx.doi.org/10.3390/molecules16097994

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