Agnostic detection of genomic alterations by holistic DNA structural interrogation

There is an established relationship between primary DNA sequence, secondary and tertiary chromatin structure, and transcriptional activity, suggesting that observed differences in one of these properties may reflect changes in the others. Here, we exploit these relationships to show that variations...

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Detalles Bibliográficos
Autores principales: Shultzaberger, Ryan K., Abrams, Rachel E., Sullivan, Challise J., Schmitt, Anthony D., Thompson, Thomas W. J., Dresios, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264503/
https://www.ncbi.nlm.nih.gov/pubmed/30496256
http://dx.doi.org/10.1371/journal.pone.0208054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264503/
https://www.ncbi.nlm.nih.gov/pubmed/30496256
http://dx.doi.org/10.1371/journal.pone.0208054

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