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Agnostic detection of genomic alterations by holistic DNA structural interrogation
There is an established relationship between primary DNA sequence, secondary and tertiary chromatin structure, and transcriptional activity, suggesting that observed differences in one of these properties may reflect changes in the others. Here, we exploit these relationships to show that variations...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264503/ https://www.ncbi.nlm.nih.gov/pubmed/30496256 http://dx.doi.org/10.1371/journal.pone.0208054 |