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Selective Covalent Conjugation of Phosphorothioate DNA Oligonucleotides with Streptavidin

Protein-DNA conjugates have found numerous applications in the field of diagnostics and nanobiotechnology, however, their intrinsic susceptibility to DNA degradation by nucleases represents a major obstacle for many applications. We here report the selective covalent conjugation of the protein strep...

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Detalles Bibliográficos
Autores principales: Rabe, Kersten S., Niemeyer, Christof M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264524/
https://www.ncbi.nlm.nih.gov/pubmed/21844841
http://dx.doi.org/10.3390/molecules16086916