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Selective Covalent Conjugation of Phosphorothioate DNA Oligonucleotides with Streptavidin
Protein-DNA conjugates have found numerous applications in the field of diagnostics and nanobiotechnology, however, their intrinsic susceptibility to DNA degradation by nucleases represents a major obstacle for many applications. We here report the selective covalent conjugation of the protein strep...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264524/ https://www.ncbi.nlm.nih.gov/pubmed/21844841 http://dx.doi.org/10.3390/molecules16086916 |