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Synthetic Routes and Biological Evaluation of Largazole and Its Analogues as Potent Histone Deacetylase Inhibitors

Natural products with interesting biological properties and structural diversity have often served as valuable lead drug candidates for the treatment of various human diseases. Largazole, isolated from the marine cyanobacterium Symploca sp. has exhibited potent inhibitory activity against many cance...

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Detalles Bibliográficos
Autores principales: Li, Shang, Yao, Hequan, Xu, Jinyi, Jiang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264525/
https://www.ncbi.nlm.nih.gov/pubmed/21654576
http://dx.doi.org/10.3390/molecules16064681