Icariside II Enhances Nrf2 Nuclear Translocation to Upregulate Phase II Detoxifying Enzyme Expression Coupled with the ERK, Akt and JNK Signaling Pathways

In the present study, the potent inducers of phase II detoxifying and antioxidant stress responsive to icariside II was investigated. First, a dose of 0–10 µM icariside II showed no significantly cytotoxicity on HepG2 cells by MTT assays and icariside II could enhance cellular GSH levels by ELISA as...

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Detalles Bibliográficos
Autores principales: Gu, Jing, Sun, Xuechao, Wang, Guonian, Li, Mingming, Chi, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264540/
https://www.ncbi.nlm.nih.gov/pubmed/22051934
http://dx.doi.org/10.3390/molecules16119234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264540/
https://www.ncbi.nlm.nih.gov/pubmed/22051934
http://dx.doi.org/10.3390/molecules16119234

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