Cargando…
Synthesis and Screening of Aromatase Inhibitory Activity of Substituted C(19) Steroidal 17-Oxime Analogs
The synthesis and aromatase inhibitory activity of androst-4-en-, androst-5-en-, 1β,2β-epoxy- and/or androsta-4,6-dien-, 4β,5β-epoxyandrostane-, and 4-substituted androst-4-en-17-oxime derivatives are described. Inhibition activity of synthesized compounds was assessed using aromatase enzyme and [1β...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264551/ https://www.ncbi.nlm.nih.gov/pubmed/22124202 http://dx.doi.org/10.3390/molecules16129868 |