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Synthesis and Screening of Aromatase Inhibitory Activity of Substituted C(19) Steroidal 17-Oxime Analogs

The synthesis and aromatase inhibitory activity of androst-4-en-, androst-5-en-, 1β,2β-epoxy- and/or androsta-4,6-dien-, 4β,5β-epoxyandrostane-, and 4-substituted androst-4-en-17-oxime derivatives are described. Inhibition activity of synthesized compounds was assessed using aromatase enzyme and [1β...

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Detalles Bibliográficos
Autores principales:	Pokhrel, Muna, Ma, Eunsook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264551/ https://www.ncbi.nlm.nih.gov/pubmed/22124202 http://dx.doi.org/10.3390/molecules16129868

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