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Synthesis of Some Oxadiazole Derivatives as New Anticandidal Agents
In this study, 5-[(pyrimidin-2-ylthio)methyl]-1,3,4-oxadiazole-2(3H)-thione (3) was synthesized via the ring closure reaction of 2-(pyrimidin-2-ylthio)acetohydrazide (2) with carbon disulphide. New oxadiazole derivatives 4a–f were obtained by the nucleophilic substitution reaction of compound 3 with...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264560/ https://www.ncbi.nlm.nih.gov/pubmed/21900868 http://dx.doi.org/10.3390/molecules16097662 |