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Succinobucol’s New Coat — Conjugation with Steroids to Alter Its Drug Effect and Bioavailability

Synthesis, detailed structural characterization (X-ray, NMR, MS, IR, elemental analysis), and studies of toxicity, antioxidant activity and bioavailability of unique potent anti-atherosclerotic succinobucol-steroid conjugates are reported. The conjugates consist of, on one side, the therapeutically...

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Detalles Bibliográficos
Autores principales: Jurček, Ondřej, Ikonen, Satu, Buřičová, Lucie, Wimmerová, Martina, Wimmer, Zdeněk, Drašar, Pavel, Horníček, Jan, Galandáková, Adéla, Ulrichová, Jitka, Kolehmainen, Erkki T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264583/
https://www.ncbi.nlm.nih.gov/pubmed/22075571
http://dx.doi.org/10.3390/molecules16119404