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Dysregulation of miR-6868-5p/FOXM1 circuit contributes to colorectal cancer angiogenesis

BACKGROUND: Transcription factor forkhead box M1 (FOXM1) is a crucial regulator in colorectal cancer (CRC) progression. However, the regulatory mechanisms causing dysregulation of FOXM1 in CRC remain unclear. METHODS: Dual-luciferase reporter assay was conducted to determine FOXM1 as miR-6868-5p tar...

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Detalles Bibliográficos
Autores principales: Wang, Ye, Wu, Meijuan, Lei, Zengjie, Huang, Mengxi, Li, Zhiping, Wang, Liya, Cao, Qijun, Han, Dong, Chang, Yue, Chen, Yanyan, Liu, Xiaobei, Xue, Lijun, Mao, Xiaobei, Geng, Jian, Chen, Yanan, Dai, Tingting, Ren, Lili, Wang, Qian, Yu, Hongju, Chen, Cheng, Chu, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264626/
https://www.ncbi.nlm.nih.gov/pubmed/30486864
http://dx.doi.org/10.1186/s13046-018-0970-5