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The Growth Suppressing Effects of Girinimbine on Hepg2 Involve Induction of Apoptosis and Cell Cycle Arrest

Murraya koenigii is an edible herb widely used in folk medicine. Here we report that girinimbine, a carbazole alkaloid isolated from this plant, inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells. The MTT and LDH assay results showed that girinimbine decreased...

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Detalles Bibliográficos
Autores principales: Syam, Suvitha, Abdul, Ahmad Bustamam, Sukari, Mohd. Aspollah, Mohan, Syam, Abdelwahab, Siddig Ibrahim, Wah, Tang Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264672/
https://www.ncbi.nlm.nih.gov/pubmed/21862957
http://dx.doi.org/10.3390/molecules16087155