Inhibitory Activity of Flavonoids against Class I Phosphatidylinositol 3-Kinase Isoforms

Class I PI3 Kinase (PI3K) phosphorylates phosphatidylinositol 4,5-bisphophate (PIP2) to generate the second messenger phosphatidylinositol 3,4,5-trisphosphate (PIP3) and therefore plays an important role in fundamental cellular responses such as proliferation. There are four isoforms of class I PI3K...

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Detalles Bibliográficos
Autores principales: Kong, Dexin, Zhang, Yanwen, Yamori, Takao, Duan, Hongquan, Jin, Meihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264676/
https://www.ncbi.nlm.nih.gov/pubmed/21694679
http://dx.doi.org/10.3390/molecules16065159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264676/
https://www.ncbi.nlm.nih.gov/pubmed/21694679
http://dx.doi.org/10.3390/molecules16065159

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