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Identification of Dehydroxytrichostatin A as a Novel Up-Regulator of the ATP-Binding Cassette Transporter A1 (ABCA1)

The ATP-binding cassette transporter A1 (ABCA1) mediates the cellular efflux of excess cholesterol and phospholipids to lipid-poor apolipoprotein A-I (apoA-I). ABCA1 plays an important role in high-density lipoprotein (HDL) biogenesis and reverse cholesterol transport. By using a cell-based screenin...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Xu, Yanni, Bao, Yi, Hong, Bin, Si, Shuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264683/
https://www.ncbi.nlm.nih.gov/pubmed/21869747
http://dx.doi.org/10.3390/molecules16097183