Camptothecin-20(s)-O-[N-(3’α,12’α-dihydroxy-24’-carbonyl-5’β-cholan)]-lysine, a Novel Camptothecin Analogue, Induces Apoptosis towards Hepatocellular Carcinoma SMMC-7721 Cells

Camptothecin-20(s)-O-[N-(3’α,12’α-dihydroxy-24’-carbonyl-5’β-cholan)]-lysine (B2) is a novel camptothecin analogue. Our previous study had shown that it displayed higher cytoxicity activity towards hepatocellular carcinoma SMMC-7721 cells than camptothecin (CPT) in vitro. In this paper, the underlyi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qingyong, Qiu, Wei, Zhu, Qiaochu, Zu, Yuangang, Deng, Xiaoqiu, Zhao, Tengfei, Jiang, Chunfei, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264744/
https://www.ncbi.nlm.nih.gov/pubmed/22143544
http://dx.doi.org/10.3390/molecules16097803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264744/
https://www.ncbi.nlm.nih.gov/pubmed/22143544
http://dx.doi.org/10.3390/molecules16097803

Ejemplares similares