Effect of ASP2151, a Herpesvirus Helicase-Primase Inhibitor, in a Guinea Pig Model of Genital Herpes

ASP2151 is a herpesvirus helicase-primase inhibitor with antiviral activity against varicella zoster virus and herpes simplex virus types 1 (HSV-1) and 2 (HSV-2). Here, we examined the potency and efficacy of ASP2151 against HSV in vitro and in vivo. We found that ASP2151 was more potent in inhibiti...

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Detalles Bibliográficos
Autores principales: Katsumata, Kiyomitsu, Chono, Koji, Sudo, Kenji, Shimizu, Yasuaki, Kontani, Toru, Suzuki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264763/
https://www.ncbi.nlm.nih.gov/pubmed/21869749
http://dx.doi.org/10.3390/molecules16097210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264763/
https://www.ncbi.nlm.nih.gov/pubmed/21869749
http://dx.doi.org/10.3390/molecules16097210

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