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Benzylidene-bis-(4-Hydroxycoumarin) and Benzopyrano-Coumarin Derivatives: Synthesis, (1)H/(13)C-NMR Conformational and X-ray Crystal Structure Studies and In Vitro Antiviral Activity Evaluations

We report on the synthesis of 4-hydroxycoumarin dimers 1–15 bearing an aryl substituent on the central linker and fused benzopyranocoumarin derivatives 16–20 and on their in vitro broad anti-DNA and RNA virus activity evaluations. The chemical identities and structure of compounds 1–20 were deduced...

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Detalles Bibliográficos
Autores principales: Završnik, Davorka, Muratović, Samija, Makuc, Damjan, Plavec, Janez, Cetina, Mario, Nagl, Ante, De Clercq, Erik, Balzarini, Jan, Mintas, Mladen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264767/
https://www.ncbi.nlm.nih.gov/pubmed/21772234
http://dx.doi.org/10.3390/molecules16076023