Docking Studies and α-Substitution Effects on the Anti-Inflammatory Activity of β-Hydroxy-β-arylpropanoic Acids

Six β-hydroxy-β-aryl propanoic acids were synthesised using a modification of Reformatsky reaction which has already been reported. These acids belong to the aryl propanoic acid class of compounds, structurally similar to the NSAIDs, such as ibuprofen, and an anti-inflammatory activity is thus expec...

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Detalles Bibliográficos
Autores principales: Savić, Jelena S., Dilber, Sanda P., Marković, Bojan D., Milenković, Marina T., Vladimirov, Sote M., Juranić, Ivan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264771/
https://www.ncbi.nlm.nih.gov/pubmed/25134768
http://dx.doi.org/10.3390/molecules16086645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264771/
https://www.ncbi.nlm.nih.gov/pubmed/25134768
http://dx.doi.org/10.3390/molecules16086645

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