DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B

Overexpression of the Dual-specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) gene contributes to the retardation, craniofacial anomalies, cognitive impairment, and learning and memory deficits associated with Down Syndrome (DS). DCAF7/HAN11/WDR68 (hereafter WDR68) binds DYRK1A and is...

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Detalles Bibliográficos
Autores principales: Yousefelahiyeh, Mina, Xu, Jingyi, Alvarado, Estibaliz, Yu, Yang, Salven, David, Nissen, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264848/
https://www.ncbi.nlm.nih.gov/pubmed/30496304
http://dx.doi.org/10.1371/journal.pone.0207779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264848/
https://www.ncbi.nlm.nih.gov/pubmed/30496304
http://dx.doi.org/10.1371/journal.pone.0207779

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