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Telomere length-dependent transcription and epigenetic modifications in promoters remote from telomere ends

Telomere-binding proteins constituting the shelterin complex have been studied primarily for telomeric functions. However, mounting evidence shows non-telomeric binding and gene regulation by shelterin factors. This raises a key question—do telomeres impact binding of shelterin proteins at distal no...

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Detalles Bibliográficos
Autores principales: Mukherjee, Ananda Kishore, Sharma, Shalu, Sengupta, Suman, Saha, Dhurjhoti, Kumar, Pankaj, Hussain, Tabish, Srivastava, Vivek, Roy, Sumitabho Deb, Shay, Jerry W., Chowdhury, Shantanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264879/
https://www.ncbi.nlm.nih.gov/pubmed/30439955
http://dx.doi.org/10.1371/journal.pgen.1007782