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Examining the current standards for genetic discovery and replication in the era of mega-biobanks

With the recent deluge of mega-biobank data, it is time to revisit what constitutes “replication” for genome-wide association studies. Many replication samples are unavailable or underpowered, therefore alternatives beyond strict statistical replication are needed until the required resources become...

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Detalles Bibliográficos
Autor principal: Huffman, J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265242/
https://www.ncbi.nlm.nih.gov/pubmed/30498205
http://dx.doi.org/10.1038/s41467-018-07348-x